Noncancerous tumors develop slowly and will become fairly giant earlier than causing symptoms. Brain tumors—whether cancerous or not—can cause serious problems as a end result of the skull is inflexible, providing no room for the tumor to expand. Chemotherapy can be used throughout and after radiotherapy as treatment for glioblastoma. Temozolomide is a Food and Drug Administration accredited therapy for the therapy of glioblastoma. Bevacizumab and Gliadel wafer are chemotherapy brokers which have also been permitted by the FDA for the treatment of glioblastoma. Bevacizumab helps scale back the variety of blood vessels to the tumor site.